pentobarbital will decrease the extent or result of etonogestrel by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.
pentobarbital will reduce the level or impact of brexpiprazole by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Check Closely. Double brexpiprazole dose about 1-2 weeks if administered with a robust CYP3A4 inducer.
pentobarbital will lower the extent or influence of finasteride by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Importance Not known.
pentobarbital will reduce the level or influence of etravirine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.
Monitor Closely (1)pentobarbital will decrease the extent or outcome of hydrocodone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep track of Closely. Caution when discontinuing CYP3A4 inducers which are coadministered with hydrocodone; plasma concentrations of hydrocodone might increase and may result in potentially deadly respiratory depressionSerious - Use Option (1)hydrocodone, pentobarbital.
pentobarbital will lower the extent or outcome of ethinylestradiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Stay away from or Use Alternate Drug. The efficacy of hormonal contraceptives can be lessened. Use of a nonhormonal contraceptive is suggested.
pentobarbital will lessen the extent or impact of theophylline by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.
pentobarbital and daridorexant both improve sedation. Modify Therapy/Monitor Intently. Coadministration boosts chance of CNS melancholy, which can result in additive impairment of psychomotor performance and result in daytime impairment.
pentobarbital will reduce the level or outcome of sulfamethoxazole by impacting hepatic enzyme CYP2C9/10 metabolism. Minor/Importance Mysterious.
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Withdrawal signs and symptoms may get more info perhaps arise from abrupt cessation right after extended use while in the dependent person and should lead to delirium, convulsions, And maybe Loss of life; barbiturates need to be withdrawn slowly from any patient regarded to become getting too much dosage in excess of long amounts of time
pentobarbital will minimize the level or result of tacrolimus by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
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pentobarbital and olopatadine intranasal both enhance sedation. Stay clear of or Use Alternate Drug. Coadministration raises threat of CNS depression, which may result in additive impairment of psychomotor overall performance and result in daytime impairment.
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